Synopsis: In a new study, researchers gave male rats Psilocybin 1 year after they sustained traumatic brain injuries. A single dose improved movement, learning & memory while restoring disrupted serotonin signaling & reducing the number of microglial cells associated with the brain’s response to injury. My take: I love
Synopsis:Â In a small study, 14 people with bipolar II depression received Psilocybin alongside psychotherapy. Depression scores improved, but 3 participants experienced notable psychiatric events, including suicidal thoughts or hypomania. The trial had no placebo group, so it cannot establish that Psilocybin caused the improvement. My take:Â People with bipolar
The “microdose” I intended on taking was definitely closer to a journey. After exploring its intense aphrodisiac qualities with a friend…I wrote a multi-page manifesto on the balcony about the direction I want to take in the next chapter of my life. Life is electric.
Welcome to The Psychedelic Blog. An independent media platform covering drugs, altered states & the culture surrounding them. This week: The FDA sketches a faster path, LSD clears another major trial, Psilocybin shows promise beyond mental health & researchers ask how you give someone a believable fake trip. Plus, the
Monday, September 14, 2026 🏛️ The FDA Wants Psychedelic Treatments to Reach Patients Faster Synopsis: The FDA is supporting faster development & review of Psychedelic medicines through priority vouchers, finalized clinical-trial guidance & new research. Its efforts include Psilocybin for depression, Methylone for PTSD & an early-stage study of
42-year-old man, Italy Found dead after using Kambo. The frog secretion peptide deltorphin A was detected in his blood. Natasha Lechner, 39, Australia, 2019 Died shortly after a Kambo ceremony. Medical experts concluded an acute coronary event was the likely cause. Jarrad Antonovich, 46, Australia, 2021 Died after
Welcome to The Psychedelic Blog. An independent media platform covering drugs, altered states & the culture surrounding them. This week: Why our definition of “sober” no longer makes sense…and what we should be asking instead. We’re all addicts. We just arbitrarily label some addictions destructive while ignoring, accepting
Independent reporting & ideas on drugs, altered states & the culture surrounding them.
Synopsis: Archaeologists studying the teeth of ancient hunter-gatherers in Indonesia found evidence that people were sucking psychoactive Betel Nuts as far back as 25,000 years ago. The discovery predates agriculture & is now considered the earliest direct evidence of habitual human drug use. My Take: I’ve said
💰 Musk’s Inner Circle Is Betting Big on Psychedelics Synopsis: 2 longtime Elon Musk allies & SpaceX directors, Antonio Gracias & Steve Jurvetson, are putting millions behind efforts to move Psychedelics into mainstream medicine. Gracias’s family foundation reportedly invested $25 million to rescue the company formerly known as Lykos
Welcome to The Psychedelic Blog. An independent media platform covering drugs, altered states & the culture surrounding them. This week: The 2nd edition of a monthly series featuring 7 questions about Psychedelics I can’t stop thinking about. 1. What if the Psychedelic Renaissance is happening in the wrong places?
I sat down with Norman Ohler, bestselling author of Blitzed: Drugs in Nazi Germany and Tripped: Nazi Germany, the CIA, and the Dawn of the Psychedelic Age, to explore a question that runs quietly through his work: the role of psychoactive substances throughout human history. Our discussion moved across time
đź’— MDMA May Work Without the Mystical Experience Synopsis: A new analysis of MDMA-assisted therapy for PTSD found that mystical experiences themselves did not significantly explain improvements in PTSD symptoms. Instead, the strongest link was positive emotional states: feelings of joy, peace & love. My Take: This is important because
The Psychedelic Blog is an independent media brand covering drugs, altered states & the culture surrounding them. This week: What happens when Psychedelics change the way you see the person you love. I wrote something about relationships that unexpectedly took off: The note wasn’t really about Greece, sharks, or
The Psychedelic Blog is an independent media brand covering drugs, altered states & the culture surrounding them. This Week: The quiet truth most people in Psychedelic spaces won’t say out loud: not everything has to heal, not everything has to be sacred, not everything has to justify itself. Sometimes
The Psychedelic Blog is an independent media brand covering drugs, altered states & the culture surrounding them. This week: Psychedelics don’t end status games…they just make them harder to see. In The Status Game, Will Storr argues that humans inevitably play status games…almost always unconsciously. The forms
The Psychedelic Blog is an independent media brand covering drugs, altered states & the culture surrounding them. This week: Why the fight to keep alcohol at the center of culture has already lost. Tomorrow will be 8 years since I quit alcohol. Around this time each year, I think about
The Psychedelic Blog is an independent media brand covering drugs, altered states & the culture surrounding them. This week: Injectable MDMA with injectable ketamine. Iboga, Bufo & mushrooms in the same weekend. Past-life certainty. At what point does exploration become escalation? A Few Recent Things Made Me Ask The